December 22, 2024

To Your Good Health: Lone Star tick bites cause alpha-gal syndrome

I was recently diagnosed with alpha-gal syndrome, or AGS. I live in the country, but I do not remember having a tick on me. My husband and I are very cautious and always check for them. I am struggling to understand what exactly are my symptoms and what I can and cannot eat. I don’t know if I am someone who can have dairy or not. The biggest challenge seems to be eating out. If I order chicken, fish or vegetables and they are cooked on the same grill as meat, then they are not safe to eat due to cross contamination. Also, dairy, lard and whey are in many food items. Is there a specialist I should consult? My doctor seems to know about some of this, but is unable to answer many of my questions. Any information you can share would be helpful.

AGS is an allergy to galactose-alpha-1,3-galactose, a carbohydrate allergen found in all mammalian meats, such as beef, pork and lamb.

The allergy can be serious as people develop symptoms, including various syndromes like skin itching and rashes; gastrointestinal symptoms; and even anaphylaxis, a severe allergy syndrome of cardiovascular collapse.

These reactions are delayed compared to other typical allergic responses, with people often developing symptoms the night after consuming meat — about two to six hours after consumption. A blood test for alpha-gal allergies can confirm the diagnosis.

These symptoms usually begin after getting bitten multiple times by a Lone Star tick. The tick has alpha-gal in its saliva, which triggers the sensitivity.

Many medical professionals are unaware of this newly described condition — 40% reported never having heard of the syndrome — which can prevent a diagnosis from being made in a timely fashion.

Because the condition is new, there are some factors that we don’t really understand about it, like why some people tolerate muscle meat from an animal, but react strongly to organ meat.

Sometimes, a person tolerates cooked meat, but is intolerant of raw or barely cooked meat. Some people lose the allergy over time — usually a few years — but additional tick bites may bring it back.

The ideal specialist in this case is an allergist. You should certainly have and know how to use an epinephrine injector in case of a severe reaction.

A dietitian recommended that I drink six glasses of water every day. I tend to drink most of the water in the morning and early afternoon. My husband thinks I should drink it “equally” throughout the day. His logic is that I don’t retain enough water to stay properly hydrated throughout the evening and night. Does timing really matter?

Your body has a system in place to hold onto water so that you don’t need to drink it during the night.

Unless you are losing unusually high amounts of water — as you would in a very dry and hot environment, for example — there is no reason to hydrate at night. Most people realize that doing so will cause you to visit the bathroom rather than sleep.

Keith Roach

Dr. Keith Roach

Dr. Roach regrets that he is unable to answer individual letters, but will incorporate them in the column whenever possible. Readers may email questions to ToYourGoodHealth@med.cornell.edu. © 2024 North America Synd., Inc.